CATH Domain 6e4lA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.130	7 Propeller
	2.130.10	Methylamine Dehydrogenase; Chain H
	2.130.10.110	Clathrin heavy-chain terminal domain

Domain Context

CATH Clusters

Superfamily	Clathrin heavy-chain terminal domain
Functional Family	Clathrin heavy chain

Enzyme Information

UniProtKB Entries (1)

CLH1_HUMAN

Homo sapiens

Clathrin heavy chain 1

PDB Structure

PDB	6E4L
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Disruption of endocytosis through chemical inhibition of clathrin heavy chain function. Dejonghe, W., Sharma, I., Denoo, B., De Munck, S., Lu, Q., Mishev, K., Bulut, H., Mylle, E., De Rycke, R., Vasileva, M., Savatin, D.V., Nerinckx, W., Staes, A., Drozdzecki, A., Audenaert, D., Yperman, K., Madder, A., Friml, J., Van Damme, D., Gevaert, K., Haucke, V., Savvides, S.N., Winne, J., Russinova, E. Nat.Chem.Biol.