CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.75 | 5-stranded Propeller | |
3.75.10 | L-arginine/glycine Amidinotransferase; Chain A | |
3.75.10.10 | L-arginine/glycine Amidinotransferase; Chain A |
Domain Context
CATH Clusters
Superfamily | L-arginine/glycine Amidinotransferase; Chain A |
Functional Family | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 |
Enzyme Information
3.5.3.18 |
Dimethylargininase.
based on mapping to UniProt O94760
N(omega),N(omega)-dimethyl-L-arginine + H(2)O = dimethylamine + L-citrulline.
-!- Also acts on N(omega)-methyl-L-arginine.
|
UniProtKB Entries (1)
O94760 |
DDAH1_HUMAN
Homo sapiens
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
|
PDB Structure
PDB | 6DGE |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Dissection, Optimization, and Structural Analysis of a Covalent Irreversible DDAH1 Inhibitor.
Biochemistry
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