CATH Classification

Domain Context

CATH Clusters

Superfamily 3.90.226.30
Functional Family

Enzyme Information

5.1.2.1
Lactate racemase.
based on mapping to UniProt F9USS9
(S)-lactate = (R)-lactate.
-!- The enzyme has been characterized from the bacterium Lactobacillus plantarum and appears to be restricted to lactic acid bacteria. -!- It contains a unique nickel-containing cofactor, pyridinium-3- thioamide-5-thiocarboxylate mononucleotide Ni pincer complex.

UniProtKB Entries (1)

F9USS9
LARA_LACPL
Lactobacillus plantarum WCFS1
Lactate racemase

PDB Structure

PDB 6C1W
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Lactate Racemase Nickel-Pincer Cofactor Operates by a Proton-Coupled Hydride Transfer Mechanism.
Rankin, J.A., Mauban, R.C., Fellner, M., Desguin, B., McCracken, J., Hu, J., Varganov, S.A., Hausinger, R.P.
Biochemistry