1 keywords

CATH Domain 6bz4B02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin heavy constant gamma 1

Enzyme Information

UniProtKB Entries (1)

P0DOX5
IGG1_HUMAN
Homo sapiens
Immunoglobulin gamma-1 heavy chain

PDB Structure

PDB 6BZ4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions.
Burvenich, I.J.G., Farrugia, W., Liu, Z., Makris, D., King, D., Gloria, B., Perani, A., Allan, L.C., Scott, A.M., Ramsland, P.A.
Biochem. J.