CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.60 | Sandwich | |
2.60.120 | Jelly Rolls | |
2.60.120.10 | Jelly Rolls |
Domain Context
CATH Clusters
Superfamily | Jelly Rolls |
Functional Family |
Enzyme Information
1.13.11.6 |
3-hydroxyanthranilate 3,4-dioxygenase.
based on mapping to UniProt Q1LCS4
3-hydroxyanthranilate + O(2) = 2-amino-3-carboxymuconate semialdehyde.
-!- The product of the reaction spontaneously rearrange to quinolinic acid (quin). -!- Formerly EC 1.13.1.6.
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UniProtKB Entries (1)
Q1LCS4 |
3HAO_CUPMC
Cupriavidus metallidurans CH34
3-hydroxyanthranilate 3,4-dioxygenase
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PDB Structure
PDB | 6BVS |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Adapting to oxygen: 3-Hydroxyanthrinilate 3,4-dioxygenase employs loop dynamics to accommodate two substrates with disparate polarities.
J. Biol. Chem.
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