CATH Classification
Level | CATH Code | Description |
---|---|---|
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2 | Mainly Beta |
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2.60 | Sandwich |
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2.60.40 | Immunoglobulin-like |
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2.60.40.1730 | tricorn interacting facor f3 domain |
Domain Context
CATH Clusters
Superfamily | tricorn interacting facor f3 domain |
Functional Family | Aminopeptidase N |
Enzyme Information
3.4.11.2 |
Membrane alanyl aminopeptidase.
based on mapping to UniProt P15145
Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.
-!- Is not activated by heavy metal ions. -!- Belongs to peptidase family M1. -!- Formerly EC 3.4.1.2, EC 3.4.3.5 and EC 3.4.13.6.
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UniProtKB Entries (1)
P15145 |
AMPN_PIG
Sus scrofa
Aminopeptidase N
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PDB Structure
PDB | 6BUY |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
The Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach.
Sci Rep
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