CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.60 | Sandwich | |
2.60.40 | Immunoglobulin-like | |
2.60.40.150 | C2 domain |
Domain Context
CATH Clusters
Superfamily | C2 domain |
Functional Family | phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta |
Enzyme Information
2.7.1.154 |
Phosphatidylinositol-4-phosphate 3-kinase.
based on mapping to UniProt O00443
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl- 1D-myo-inositol 3,4-bisphosphate.
-!- This enzyme also phosphorylates PtdIns to PtdIns3P.
|
UniProtKB Entries (1)
O00443 |
P3C2A_HUMAN
Homo sapiens
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
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PDB Structure
PDB | 6BTZ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure
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