CATH Classification

Domain Context

CATH Clusters

Superfamily C2 domain
Functional Family phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

Enzyme Information

2.7.1.154
Phosphatidylinositol-4-phosphate 3-kinase.
based on mapping to UniProt O00443
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl- 1D-myo-inositol 3,4-bisphosphate.
-!- This enzyme also phosphorylates PtdIns to PtdIns3P.

UniProtKB Entries (1)

O00443
P3C2A_HUMAN
Homo sapiens
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

PDB Structure

PDB 6BTZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Chen, K.E., Tillu, V.A., Chandra, M., Collins, B.M.
Structure