CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.150.810
Functional Family DNA polymerase kappa

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q9UBT6
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q9UBT6
POLK_HUMAN
Homo sapiens
DNA polymerase kappa

PDB Structure

PDB 6BS1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender.
Jha, V., Ling, H.
J. Mol. Biol.