CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.150 | DNA polymerase; domain 1 | |
1.10.150.810 |
Domain Context
CATH Clusters
Superfamily | 1.10.150.810 |
Functional Family | DNA polymerase kappa |
Enzyme Information
2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt Q9UBT6
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
|
UniProtKB Entries (1)
Q9UBT6 |
POLK_HUMAN
Homo sapiens
DNA polymerase kappa
|
PDB Structure
PDB | 6BS1 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender.
J. Mol. Biol.
|