CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.1170 | Mu homology domain, subdomain B |
Domain Context
CATH Clusters
| Superfamily | Mu homology domain, subdomain B |
| Functional Family | AP-2 complex subunit mu isoform 2 |
Enzyme Information
UniProtKB Entries (1)
| P35568 |
IRS1_HUMAN
Homo sapiens
Insulin receptor substrate 1
|
PDB Structure
| PDB | 6BNT |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling.
Nat Commun
|
