CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
4 | Few Secondary Structures |
|
4.10 | Irregular |
|
4.10.170 | p53, subunit A |
|
4.10.170.10 | p53-like tetramerisation domain |
Domain Context
CATH Clusters
| Superfamily | p53-like tetramerisation domain |
| Functional Family | serine/threonine-protein kinase 3 |
Enzyme Information
| 2.7.11.1 |
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q8T0S6
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
|
UniProtKB Entries (1)
| Q8T0S6 |
HIPPO_DROME
Drosophila melanogaster
Serine/threonine-protein kinase hippo
|
PDB Structure
| PDB | 6BN1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Salvador has an extended SARAH domain that mediates binding to Hippo kinase.
J. Biol. Chem.
|
