CATH Domain 6bmqA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.10860	Leucine Dehydrogenase, chain A, domain 1

Domain Context

CATH Clusters

Superfamily	Leucine Dehydrogenase, chain A, domain 1
Functional Family	Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic

Enzyme Information

4.2.1.10	3-dehydroquinate dehydratase. based on mapping to UniProt Q9SQT8 3-dehydroquinate = 3-dehydroshikimate + H(2)O.
1.1.1.25	Shikimate dehydrogenase. based on mapping to UniProt Q9SQT8 Shikimate + NADP(+) = 3-dehydroshikimate + NADPH. -!- NAD(+) cannot replace NADP(+). -!- In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.

UniProtKB Entries (1)

DHQSD_ARATH

Arabidopsis thaliana

Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic

PDB Structure

PDB	6BMQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and biochemical approaches uncover multiple evolutionary trajectories of plant quinate dehydrogenases. Gritsunov, A., Peek, J., Diaz Caballero, J., Guttman, D., Christendat, D. Plant J.