CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family Rho guanine nucleotide exchange factor 2

Enzyme Information

UniProtKB Entries (1)

Q8N1W1
ARG28_HUMAN
Homo sapiens
Rho guanine nucleotide exchange factor 28

PDB Structure

PDB 6BC1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
Dada, O., Gutowski, S., Brautigam, C.A., Chen, Z., Sternweis, P.C.
J. Struct. Biol.