CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.90 | Alpha-Beta Complex |
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3.90.190 | Protein-Tyrosine Phosphatase; Chain A |
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3.90.190.10 | Protein tyrosine phosphatase superfamily |
Domain Context
CATH Clusters
Superfamily | Protein tyrosine phosphatase superfamily |
Functional Family | Tyrosine-protein phosphatase non-receptor type 1 |
Enzyme Information
3.1.3.48 |
Protein-tyrosine-phosphatase.
based on mapping to UniProt P18031
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.
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UniProtKB Entries (1)
P18031 |
PTN1_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 1
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PDB Structure
PDB | 6B8T |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.
Elife
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