CATH Domain 6a8vB00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.450	Beta-Lactamase
	3.30.450.140	PhoQ sensor domain

Domain Context

CATH Clusters

Superfamily	3.30.450.140
Functional Family	Virulence sensor histidine kinase PhoQ

Enzyme Information

2.7.13.3	Histidine kinase. based on mapping to UniProt P23837 ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. -!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.
3.1.3.-	Phosphoric monoester hydrolases. based on mapping to UniProt P23837

UniProtKB Entries (1)

PHOQ_ECOLI

Escherichia coli K-12

Sensor protein PhoQ

PDB Structure

PDB	6A8V
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification of an internal cavity in the PhoQ sensor domain for PhoQ activity and SafA-mediated control. Yoshitani, K., Ishii, E., Taniguchi, K., Sugimoto, H., Shiro, Y., Akiyama, Y., Kato, A., Utsumi, R., Eguchi, Y. Biosci. Biotechnol. Biochem.