CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1820 | alpha/beta hydrolase |
Domain Context
CATH Clusters
| Superfamily | alpha/beta hydrolase |
| Functional Family | Monoglyceride lipase |
Enzyme Information
| 3.1.1.23 |
Acylglycerol lipase.
based on mapping to UniProt Q99685
Hydrolyzes glycerol monoesters of long-chain fatty acids.
|
UniProtKB Entries (1)
| Q99685 |
MGLL_HUMAN
Homo sapiens
Monoglyceride lipase
|
PDB Structure
| PDB | 5ZUN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors
J. Med. Chem.
|