1 keywords

CATH Domain 5zi4B02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.110 L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2
Homologous Superfamily 3.90.110.10 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family Malate dehydrogenase

Enzyme Information

1.1.1.37
Malate dehydrogenase.
based on mapping to UniProt P32419
(S)-malate + NAD(+) = oxaloacetate + NADH.
-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

P32419
MDHP_YEAST
Saccharomyces cerevisiae S288C
Malate dehydrogenase, peroxisomal

PDB Structure

PDB 5ZI4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of glyoxysomal malate dehydrogenase (MDH3) from Saccharomyces cerevisiae.
Moriyama, S., Nishio, K., Mizushima, T.
Acta Crystallogr F Struct Biol Commun