CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.170 | Beta Complex |
|
2.170.270 | Beta-clip-like |
|
2.170.270.10 | SET domain |
Domain Context
CATH Clusters
| Superfamily | SET domain |
| Functional Family | Histone-lysine N-methyltransferase SETD7 |
Enzyme Information
| 2.1.1.43 |
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q8WTS6
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
|
UniProtKB Entries (1)
| Q8WTS6 |
SETD7_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase SETD7
|
PDB Structure
| PDB | 5YLT |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Development of Novel Inhibitors for Histone Methyltransferase SET7/9 based on Cyproheptadine.
ChemMedChem
|
