CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.1050 | Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 |
|
1.20.1050.10 |
Domain Context
CATH Clusters
| Superfamily | 1.20.1050.10 |
| Functional Family | Methionine--tRNA ligase, cytoplasmic |
Enzyme Information
| 6.1.1.10 |
Methionine--tRNA ligase.
based on mapping to UniProt P56192
ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met).
-!- In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9.
|
UniProtKB Entries (1)
| P07814 |
SYEP_HUMAN
Homo sapiens
Bifunctional glutamate/proline--tRNA ligase
|
PDB Structure
| PDB | 5Y6L |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A subcomplex crystal structure of human cytosolic aspartyl-tRNA synthetase and heterotetrameric glutathione transferase-homology domains in multi-tRNA synthetase complex
To be published
|