CATH Domain 5y12A00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.128	Lipocalin
	2.40.128.20	Calycin beta-barrel core domain

Domain Context

CATH Clusters

Superfamily	2.40.128.20
Functional Family	Fatty acid-binding protein, adipocyte

Enzyme Information

UniProtKB Entries (1)

FABP4_HUMAN

Homo sapiens

Fatty acid-binding protein, adipocyte

PDB Structure

PDB	5Y12
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4 Gao, D.D., Dou, H.X., Su, H.X., Zhang, M.M., Wang, T., Liu, Q.F., Cai, H.Y., Ding, H.P., Yang, Z., Zhu, W.L., Xu, Y.C., Wang, H.Y., Li, Y.X. Eur J Med Chem