CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.20 | Up-down Bundle | |
1.20.58 | Methane Monooxygenase Hydroxylase; Chain G, domain 1 | |
1.20.58.1610 | NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 |
Domain Context
CATH Clusters
Superfamily | NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 |
Functional Family | NADH-quinone oxidoreductase subunit A |
Enzyme Information
7.1.1.2 |
NADH:ubiquinone reductase (H(+)-translocating).
based on mapping to UniProt P03897
NADH + ubiquinone + 5 H(+)(In) = NAD(+) + ubiquinol + 4 H(+)(Out).
-!- The complex is present in mitochondria and aerobic bacteria. -!- Breakdown of the complex can release EC 1.6.99.3. -!- In photosynthetic bacteria, reversed electron transport through this enzyme can reduce NAD(+) to NADH. -!- Formerly EC 1.6.5.3.
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UniProtKB Entries (1)
P03901 |
NU4LM_HUMAN
Homo sapiens
NADH-ubiquinone oxidoreductase chain 4L
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PDB Structure
PDB | 5XTD |
External Links | |
Method | ELECTRON MICROSCOPY |
Organism | |
Primary Citation |
Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell
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