CATH Domain 5xmaB02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.210	Beta Polymerase; domain 3
	3.30.210.10	DNA polymerase, thumb domain

Domain Context

CATH Clusters

Superfamily	DNA polymerase, thumb domain
Functional Family	Repair DNA polymerase X

Enzyme Information

2.7.7.7

DNA-directed DNA polymerase.

based on mapping to UniProt P42494

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P42494

DPOLX_ASFB7

African swine fever virus BA71V

Repair DNA polymerase X

PDB Structure

PDB	5XMA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of an RNA-cleaving DNAzyme. Liu, H., Yu, X., Chen, Y., Zhang, J., Wu, B., Zheng, L., Haruehanroengra, P., Wang, R., Li, S., Lin, J., Li, J., Sheng, J., Huang, Z., Ma, J., Gan, J. Nat Commun