CATH Domain 5xleS02

CATH Classification

Level	CATH Code	Description
	4	Few Secondary Structures
	4.10	Irregular
	4.10.480	Cytochrome-c3 Hydrogenase; Chain A, domain 2
	4.10.480.10	Cytochrome-c3 hydrogenase, C-terminal domain

Domain Context

CATH Clusters

Superfamily	Cytochrome-c3 hydrogenase, C-terminal domain
Functional Family

Enzyme Information

1.12.2.1

Cytochrome-c3 hydrogenase.

based on mapping to UniProt P21853

H(2) + 2 ferricytochrome c3 = 2 H(+) + 2 ferrocytochrome c3.

-!- Some forms of the enzyme contain nickel ([NiFe]-hydrogenases) and, of these, some contain selenocysteine ([NiFeSe]-hydrogenases). -!- Methylene blue and other acceptors can also be reduced.

UniProtKB Entries (1)

P21853

PHNS_DESVM

Desulfovibrio vulgaris str. 'Miyazaki F'

Periplasmic [NiFe] hydrogenase small subunit

PDB Structure

PDB	5XLE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Ni-elimination from the active site of the standard [NiFe]‐hydrogenase upon oxidation by O2. Nishikawa, K., Mochida, S., Hiromoto, T., Shibata, N., Higuchi, Y. J. Inorg. Biochem.