CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1220 | TPP-binding domain |
Domain Context
CATH Clusters
| Superfamily | TPP-binding domain |
| Functional Family | Acetolactate synthase |
Enzyme Information
| 2.2.1.6 |
Acetolactate synthase.
based on mapping to UniProt P07342
2 pyruvate = 2-acetolactate + CO(2).
-!- The reaction shown is in the pathway of biosynthesis of valine. -!- The enzyme can also transfer the acetaldehyde from pyruvate to 2-oxobutanoate, forming 2-ethyl-2-hydroxy-3-oxobutanoate, also known as 2-aceto-2-hydroxybutanoate, a reaction in the biosynthesis of isoleucine. -!- Formerly EC 4.1.3.18.
|
UniProtKB Entries (1)
| P07342 |
ILVB_YEAST
Saccharomyces cerevisiae S288C
Acetolactate synthase catalytic subunit, mitochondrial
|
PDB Structure
| PDB | 5WKC |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural insights into the mechanism of inhibition of AHAS by herbicides.
Proc. Natl. Acad. Sci. U.S.A.
|