CATH Classification

Domain Context

CATH Clusters

Superfamily Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family Ornithine aminotransferase

Enzyme Information

2.6.1.13
Ornithine aminotransferase.
based on mapping to UniProt P04181
L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.

UniProtKB Entries (1)

P04181
OAT_HUMAN
Homo sapiens
Ornithine aminotransferase, mitochondrial

PDB Structure

PDB 5VWO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5'-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover.
Mascarenhas, R., Le, H.V., Clevenger, K.D., Lehrer, H.J., Ringe, D., Kelleher, N.L., Silverman, R.B., Liu, D.
Biochemistry