CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.420 | Nucleotidyltransferase; domain 5 |
|
3.30.420.10 | Ribonuclease H-like superfamily/Ribonuclease H |
Domain Context
CATH Clusters
| Superfamily | Ribonuclease H-like superfamily/Ribonuclease H |
| Functional Family | Protein RISC-INTERACTING CLEARING 3'-5' EXORIBONUCLEASE 2 |
Enzyme Information
| 3.1.13.1 |
Exoribonuclease II.
based on mapping to UniProt Q9SF21
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.
-!- Preference for single-stranded RNA. -!- The enzyme processes 3'-terminal extra-nucleotides of monomeric tRNA precursors, following the action of EC 3.1.26.5. -!- Similar enzymes: RNase Q, RNase BN, RNase PIII, RNase Y. -!- Formerly EC 3.1.4.20.
|
UniProtKB Entries (1)
| Q9SF21 |
RICE1_ARATH
Arabidopsis thaliana
Protein RISC-INTERACTING CLEARING 3'-5' EXORIBONUCLEASE 1
|
PDB Structure
| PDB | 5V5F |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
RISC-interacting clearing 3'- 5' exoribonucleases (RICEs) degrade uridylated cleavage fragments to maintain functional RISC in Arabidopsis thaliana.
Elife
|