CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.580 | Citrate Synthase; domain 1 |
|
1.10.580.10 | Citrate Synthase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Citrate Synthase, domain 1 |
| Functional Family | Citrate synthase |
Enzyme Information
| 2.3.3.1 |
Citrate (Si)-synthase.
based on mapping to UniProt O75390
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.
-!- The stereospecificity of this enzyme is opposite to that of EC 2.3.3.3, which is found in some anaerobes. -!- Citrate synthase for which the stereospecificity with respect to C(2) of oxaloacetate has not been established are included in EC 2.3.3.16. -!- Formerly EC 4.1.3.7.
|
UniProtKB Entries (1)
| O75390 |
CISY_HUMAN
Homo sapiens
Citrate synthase, mitochondrial
|
PDB Structure
| PDB | 5UZR |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural and functional characterization of 2-methylcitrate synthase (mcsA) from Aspergillus fumigatus and citrate synthase (hCS) from Homo sapiens.
To Be Published
|