CATH Domain 5ttzA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.565	Heat Shock Protein 90
	3.30.565.10	Histidine kinase-like ATPase, C-terminal domain

Domain Context

CATH Clusters

Superfamily	Histidine kinase-like ATPase, C-terminal domain
Functional Family	Heat shock protein 90

Enzyme Information

UniProtKB Entries (1)

ENPL_CANLF

Canis lupus familiaris

Endoplasmin

PDB Structure

PDB	5TTZ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma. Stothert, A.R., Suntharalingam, A., Tang, X., Crowley, V.M., Mishra, S.J., Webster, J.M., Nordhues, B.A., Huard, D.J.E., Passaglia, C.L., Lieberman, R.L., Blagg, B.S.J., Blair, L.J., Koren, J., Dickey, C.A. Sci Rep