CATH Domain 5ts2B00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.620	HUPs

Domain Context

CATH Clusters

Superfamily	HUPs
Functional Family

Enzyme Information

2.7.7.3

Pantetheine-phosphate adenylyltransferase.

based on mapping to UniProt B7V2S6

ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA.

-!- The enzyme from several bacteria (e.g. Escherichia coli, Bacillus subtilis and Haemophilus influenzae) has been shown to be bifunctional and also to possess the activity of EC 2.3.1.157.

UniProtKB Entries (1)

B7V2S6

COAD_PSEA8

Pseudomonas aeruginosa LESB58

Phosphopantetheine adenylyltransferase

PDB Structure

PDB	5TS2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of a phosphopantetheine adenylyltransferase (CoaD, PPAT) from Pseudomonas aeruginosa bound to dephospho coenzyme A Edwards, T.E., Davies, D.R., Fairman, J.W., Lorimer, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) To Be Published