CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.120.200
Functional Family Botulinum neurotoxin type A

Enzyme Information

3.4.24.69
Bontoxilysin.
based on mapping to UniProt P0DPI1
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.

UniProtKB Entries (1)

P0DPI1
BXA1_CLOBH
Clostridium botulinum A str. Hall
Botulinum neurotoxin type A

PDB Structure

PDB 5TPC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Glycans Confer Specificity to the Recognition of Ganglioside Receptors by Botulinum Neurotoxin A.
Hamark, C., Berntsson, R.P., Masuyer, G., Henriksson, L.M., Gustafsson, R., Stenmark, P., Widmalm, G.
J. Am. Chem. Soc.