CATH Classification

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family Basic phospholipase A2 homolog

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P20474
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P20474
PA2B3_BOTAS
Bothrops asper
Basic phospholipase A2 myotoxin III

PDB Structure

PDB 5TFV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative "myotoxic cluster".
Salvador, G.H., Dos Santos, J.I., Lomonte, B., Fontes, M.R.
Biochimie