CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.20 | Up-down Bundle | |
1.20.90 | Phospholipase A2 | |
1.20.90.10 | Phospholipase A2 domain |
Domain Context
CATH Clusters
Superfamily | Phospholipase A2 domain |
Functional Family | Basic phospholipase A2 homolog |
Enzyme Information
3.1.1.4 |
Phospholipase A(2).
based on mapping to UniProt P20474
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.
|
UniProtKB Entries (1)
P20474 |
PA2B3_BOTAS
Bothrops asper
Basic phospholipase A2 myotoxin III
|
PDB Structure
PDB | 5TFV |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative "myotoxic cluster".
Biochimie
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