CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.10 | Ribbon |
|
2.10.90 | Cystine Knot Cytokines, subunit B |
|
2.10.90.10 | Cystine-knot cytokines |
Domain Context
CATH Clusters
| Superfamily | Cystine-knot cytokines |
| Functional Family | Vascular endothelial growth factor A |
Enzyme Information
UniProtKB Entries (1)
| P0DOX5 |
IGG1_HUMAN
Homo sapiens
Immunoglobulin gamma-1 heavy chain
|
PDB Structure
| PDB | 5O4E |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 angstrom crystal structure of the complex.
MAbs
|