CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.220 | Leucine Aminopeptidase, subunit E; domain 1 |
|
3.40.220.10 | Leucine Aminopeptidase, subunit E, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Leucine Aminopeptidase, subunit E, domain 1 |
| Functional Family | Poly [ADP-ribose] polymerase |
Enzyme Information
| 2.4.2.- |
Pentosyltransferases.
based on mapping to UniProt Q460N5
|
UniProtKB Entries (1)
| Q460N5 |
PAR14_HUMAN
Homo sapiens
Protein mono-ADP-ribosyltransferase PARP14
|
PDB Structure
| PDB | 5O2D |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Discovery of a Selective Allosteric Inhibitor Targeting Macrodomain 2 of Polyadenosine-Diphosphate-Ribose Polymerase 14.
ACS Chem. Biol.
|