CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.80 | Glycosidases |
Domain Context
CATH Clusters
| Superfamily | Glycosidases |
| Functional Family | Oligosaccharide 4-alpha-D-glucosyltransferase |
Enzyme Information
| 2.4.1.161 |
Oligosaccharide 4-alpha-D-glucosyltransferase.
based on mapping to UniProt B3PEE6
Transfers the non-reducing terminal alpha-D-glucose residue from a (1->4)-alpha-D-glucan to the 4-position of a free glucose or of a glucosyl residue at the non-reducing terminus of a (1->4)-alpha-D-glucan, thus bringing about the rearrangement of oligosaccharides.
-!- The enzyme acts on amylose, amylopectin, glycogen and maltooligosaccharides. -!- No detectable free glucose is formed, indicating the enzyme does not act as a hydrolase. -!- The enzyme from the bacterium Cellvibrio japonicus has the highest activity with maltotriose as a donor, and also accepts maltose, while the enzyme from amoeba does not accept maltose. -!- Oligosaccharides with 1->6 linkages cannot function as donors, but can act as acceptors. -!- Unlike EC 2.4.1.25, this enzyme can transfer only a single glucosyl residue.
|
UniProtKB Entries (1)
| B3PEE6 |
OL4AG_CELJU
Cellvibrio japonicus Ueda107
Oligosaccharide 4-alpha-D-glucosyltransferase
|
PDB Structure
| PDB | 5NPE |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor.
ACS Cent Sci
|
