CATH Classification

Domain Context

CATH Clusters

Superfamily Bira Bifunctional Protein; Domain 2
Functional Family Phenylalanyl-tRNA synthetase 2, mitochondrial

Enzyme Information

6.1.1.20
Phenylalanine--tRNA ligase.
based on mapping to UniProt O95363
ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl- tRNA(Phe).

UniProtKB Entries (1)

O95363
SYFM_HUMAN
Homo sapiens
Phenylalanine--tRNA ligase, mitochondrial

PDB Structure

PDB 5MGW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Kinetic and structural changes in HsmtPheRS, induced by pathogenic mutations in human FARS2.
Kartvelishvili, E., Tworowski, D., Vernon, H., Moor, N., Wang, J., Wong, L.J., Chrzanowska-Lightowlers, Z., Safro, M.
Protein Sci.
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