CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1110 | SGNH hydrolase |
Domain Context
CATH Clusters
| Superfamily | SGNH hydrolase |
| Functional Family | Lipase 1 |
Enzyme Information
| 3.1.2.2 |
Palmitoyl-CoA hydrolase.
based on mapping to UniProt Q93MW7
Palmitoyl-CoA + H(2)O = CoA + palmitate.
-!- Also hydrolyzes CoA thioesters of other long-chain fatty acids.
|
| 3.1.1.3 |
Triacylglycerol lipase.
based on mapping to UniProt Q93MW7
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
-!- The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.
|
| 3.1.1.- |
Carboxylic ester hydrolases.
based on mapping to UniProt Q93MW7
|
UniProtKB Entries (1)
| Q93MW7 |
LIP_STRRM
Streptomyces rimosus
Lipase
|
PDB Structure
| PDB | 5MAL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Catalytic Dyad in the SGNH Hydrolase Superfamily: In-depth Insight into Structural Parameters Tuning the Catalytic Process of Extracellular Lipase from Streptomyces rimosus.
ACS Chem. Biol.
|