CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.50.90
Functional Family Staphylococcal nuclease domain-containing protein

Enzyme Information

3.1.31.1
Micrococcal nuclease.
based on mapping to UniProt Q7KZF4
Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products.
-!- Hydrolyzes double- or single-stranded substrate. -!- Similar enzymes: Chlamydomonas nuclease, spleen phosphodiesterase, spleen endonuclease. -!- Formerly EC 3.1.4.7.

UniProtKB Entries (1)

Q01094
E2F1_HUMAN
Homo sapiens
Transcription factor E2F1

PDB Structure

PDB 5M9O
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of human SND1 extended Tudor domain in complex with a symmetrically dimethylated E2F peptide
Tallant, C., Savitsky, P., Moehlenbrink, J., Chan, C., Nunez-Alonso, G., Siejka, P., Sorrell, F.J., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Fedorov, O., La Thangue, N.B., Knapp, S.
To Be Published