CATH Domain 5lz4A00

Superfamily	alpha/beta hydrolase
Functional Family	Platelet-activating factor acetylhydrolase

3.1.1.47

1-alkyl-2-acetylglycerophosphocholine esterase.

based on mapping to UniProt Q13093

1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H(2)O = 1-alkyl- sn-glycero-3-phosphocholine + acetate.

PAFA_HUMAN

Homo sapiens

Platelet-activating factor acetylhydrolase

PDB	5LZ4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2). Woolford, A.J., Day, P.J., Beneton, V., Berdini, V., Coyle, J.E., Dudit, Y., Grondin, P., Huet, P., Lee, L.Y., Manas, E.S., McMenamin, R.L., Murray, C.W., Page, L.W., Patel, V.K., Potvain, F., Rich, S.J., Sang, Y., Somers, D.O., Trottet, L., Wan, Z., Zhang, X. J. Med. Chem.