CATH Domain 5lsoA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.330	RRM (RNA recognition motif) domain

Domain Context

CATH Clusters

Superfamily	3.30.70.330
Functional Family	Putative splicing factor 45

Enzyme Information

UniProtKB Entries (1)

SPF45_HUMAN

Homo sapiens

Splicing factor 45

PDB Structure

PDB	5LSO
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing. Jagtap, P.K., Garg, D., Kapp, T.G., Will, C.L., Demmer, O., Luhrmann, R., Kessler, H., Sattler, M. J. Med. Chem.