CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Acetylcholinesterase

Enzyme Information

3.1.1.8
Cholinesterase.
based on mapping to UniProt P06276
An acylcholine + H(2)O = choline + a carboxylate.
-!- Acts on a variety of choline esters and a few other compounds.

UniProtKB Entries (1)

P06276
CHLE_HUMAN
Homo sapiens
Cholinesterase

PDB Structure

PDB 5LKR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents.
Kosak, U., Knez, D., Coquelle, N., Brus, B., Pislar, A., Nachon, F., Brazzolotto, X., Kos, J., Colletier, J.P., Gobec, S.
Bioorg. Med. Chem.
CATH-Gene3D is a Global Biodata Core Resource Learn more...