CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.10.160
Functional Family RecBCD enzyme subunit RecC

Enzyme Information

3.1.11.5
Exodeoxyribonuclease V.
based on mapping to UniProt P07648
Exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides.
-!- Preference for double-stranded DNA. -!- Possesses DNA-dependent ATPase activity. -!- Acts endonucleolytically on single-stranded circular DNA. -!- Similar enzyme: Haemophilus influenzae ATP-dependent DNase.

UniProtKB Entries (1)

P04993
RECD_ECOLI
Escherichia coli K-12
RecBCD enzyme subunit RecD

PDB Structure

PDB 5LD2
External Links
Method ELECTRON MICROSCOPY
Organism
Primary Citation
Mechanism for nuclease regulation in RecBCD.
Wilkinson, M., Chaban, Y., Wigley, D.B.
Elife
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