CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome P450
Functional Family Cytochrome P450 monooxygenase

Enzyme Information

1.14.19.8
Pentalenolactone synthase.
based on mapping to UniProt E3VWI3
Pentalenolactone F + O(2) + 2 reduced ferredoxin + 2 H(+) = pentalenolactone + 2 oxidized ferredoxin + 2 H(2)O.
-!- Isolated from the bacteria Streptomyces exfoliatus and Streptomyces arenae. -!- Formerly EC 1.3.7.10.

UniProtKB Entries (1)

E3VWI3
PNTM_STRAE
Streptomyces arenae
Pentalenolactone synthase

PDB Structure

PDB 5L1V
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism.
Duan, L., Jogl, G., Cane, D.E.
J.Am.Chem.Soc.
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