CATH Classification

Domain Context

CATH Clusters

Superfamily Calcium-transporting ATPase, cytoplasmic domain N
Functional Family Plasma membrane ATPase

Enzyme Information

7.1.2.1
P-type H(+)-exporting transporter.
based on mapping to UniProt P19456
ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out).
-!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- This enzyme occurs in protozoa, fungi and plants, and generates an electrochemical potential gradient of protons across the plasma membrane. -!- Formerly EC 3.6.1.35 and EC 3.6.3.6.

UniProtKB Entries (1)

P19456
PMA2_ARATH
Arabidopsis thaliana
ATPase 2, plasma membrane-type

PDB Structure

PDB 5KSD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Improved Model of Proton Pump Crystal Structure Obtained by Interactive Molecular Dynamics Flexible Fitting Expands the Mechanistic Model for Proton Translocation in P-Type ATPases.
Focht, D., Croll, T.I., Pedersen, B.P., Nissen, P.
Front Physiol
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