CATH Classification

Domain Context

CATH Clusters

Superfamily Cupin
Functional Family Lysine-specific demethylase 4D

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt Q9H3R0

UniProtKB Entries (1)

Q9H3R0
KDM4C_HUMAN
Homo sapiens
Lysine-specific demethylase 4C

PDB Structure

PDB 5KR7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of potent, selective KDM5 inhibitors.
Gehling, V.S., Bellon, S.F., Harmange, J.C., LeBlanc, Y., Poy, F., Odate, S., Buker, S., Lan, F., Arora, S., Williamson, K.E., Sandy, P., Cummings, R.T., Bailey, C.M., Bergeron, L., Mao, W., Gustafson, A., Liu, Y., VanderPorten, E., Audia, J.E., Trojer, P., Albrecht, B.K.
Bioorg.Med.Chem.Lett.
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