CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | V-type proton ATPase catalytic subunit A |
Enzyme Information
| 7.2.2.1 |
Na(+)-transporting two-sector ATPase.
based on mapping to UniProt Q08636
ATP + H(2)O + n Na(+)(Side 1) = ADP + phosphate + n Na(+)(Side 2).
-!- A multisubunit ATPase transporter found in some halophilic or alkalophilic bacteria that functions in maintaining sodium homeostasis. -!- The enzyme is similar to EC 7.1.2.2 but pumps Na(+) rather than H(+). -!- Cf. EC 7.2.2.3 and EC 7.2.2.4. -!- Formerly EC 3.6.3.15.
|
UniProtKB Entries (1)
| Q08637 |
NTPB_ENTHA
Enterococcus hirae ATCC 9790
V-type sodium ATPase subunit B
|
PDB Structure
| PDB | 5KNB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of the ATP-binding and ADP-release dwells of the V1 rotary motor
Nat Commun
|
