CATH Classification

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family L-lactate dehydrogenase A chain

Enzyme Information

1.1.1.27
L-lactate dehydrogenase.
based on mapping to UniProt P13491
(S)-lactate + NAD(+) = pyruvate + NADH.
-!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids. -!- NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.

UniProtKB Entries (1)

P13491
LDHA_RABIT
Oryctolagus cuniculus
L-lactate dehydrogenase A chain

PDB Structure

PDB 5KKC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Ligand binding phenomena that pertain to the metabolic function of renalase.
Beaupre, B.A., Roman, J.V., Hoag, M.R., Meneely, K.M., Silvaggi, N.R., Lamb, A.L., Moran, G.R.
Arch.Biochem.Biophys.