CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.90 | Alpha-Beta Complex | |
3.90.226 | 2-enoyl-CoA Hydratase; Chain A, domain 1 | |
3.90.226.10 | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
Domain Context
CATH Clusters
Superfamily | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
Functional Family | (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase |
Enzyme Information
1.13.11.80 |
(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase.
based on mapping to UniProt Q8KLK7
(3,5-dihydroxyphenyl)acetyl-CoA + O(2) = 2-(3,5-dihydroxyphenyl)-2- oxoacetate + CoA.
-!- The enzyme, characterized from bacteria Streptomyces toyocaensis and Amycolatopsis orientalis, is involved in the biosynthesis of (3,5- dihydroxyphenyl)glycine, a component of the glycopeptide antibiotic vancomycin.
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UniProtKB Entries (1)
Q8KLK7 |
DPGC_STRTO
Streptomyces toyocaensis
(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase
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PDB Structure
PDB | 5KAJ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Probing the structural basis of oxygen binding in a cofactor-independent dioxygenase.
Acta Crystallogr D Struct Biol
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