CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family protein tyrosine phosphatase type IVA 1

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q12974
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q12974
TP4A2_HUMAN
Homo sapiens
Protein tyrosine phosphatase type IVA 2

PDB Structure

PDB 5K22
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Phosphocysteine in the PRL-CNNM pathway mediates magnesium homeostasis.
Gulerez, I., Funato, Y., Wu, H., Yang, M., Kozlov, G., Miki, H., Gehring, K.
EMBO Rep.