CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1100 |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.1100 |
| Functional Family | Cysteine synthase |
Enzyme Information
| 4.5.1.5 |
S-carboxymethylcysteine synthase.
based on mapping to UniProt P0ABK6
3-chloro-L-alanine + thioglycolate = S-carboxymethyl-L-cysteine + chloride.
|
| 2.5.1.47 |
Cysteine synthase.
based on mapping to UniProt P0ABK6
O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
-!- Some alkyl thiols, cyanide, pyrazole and some other heterocyclic compounds can act as acceptors. -!- Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53. -!- Formerly EC 4.2.99.8.
|
UniProtKB Entries (2)
| Q0T963 |
CDIA_ECOL5
Escherichia coli 536
TRNA nuclease CdiA
|
| P0ABK6 |
CYSK_ECO57
Escherichia coli O157:H7
Cysteine synthase A
|
PDB Structure
| PDB | 5J43 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Unraveling the essential role of CysK in CDI toxin activation.
Proc. Natl. Acad. Sci. U.S.A.
|