CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.70 | Distorted Sandwich |
|
2.70.130 | Cation-dependent Mannose-6-phosphate Receptor; Chain A |
|
2.70.130.10 | Mannose-6-phosphate receptor binding domain |
Domain Context
CATH Clusters
| Superfamily | Mannose-6-phosphate receptor binding domain |
| Functional Family | Insulin-like growth factor 2 receptor |
Enzyme Information
UniProtKB Entries (1)
| P11717 |
MPRI_HUMAN
Homo sapiens
Cation-independent mannose-6-phosphate receptor
|
PDB Structure
| PDB | 5IEI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Proc.Natl.Acad.Sci.USA
|